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Gene Name CYP1A1 Uniprot ID P04798 Uniprot Name Cytochrome P450 1A1 Molecular Weight 58164.815 Da References Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database. PubMed: Yazawa K, Wang JW, Hao LY, Onoue Y, canada Kameyama M: Verrucotoxin, a stonefish venom, modulates calcium channel activity in guinea-pig ventricular myocytes. Bedford Labs Ben Venue Laboratories Inc. The propranolol beta-2-adrenergic receptor binds epinephrine with an approximately. (R)-warfarin The metabolism of (R)-warfarin can be propranolol decreased when combined with Propranolol. Ships Worldwide with some restrictions from Canada, India, Mauritius, NZ, Turkey,. PubMed: Masubuchi Y, Hosokawa S, Horie T, Suzuki T, Ohmori S, Kitada M, Narimatsu propranolol S: Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. Doi: Epub 2010 Mar. 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Gene Name CYP3A4 Uniprot ID P08684 Uniprot Name Cytochrome P450 3A4 Molecular Weight 57342.67 Da References Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database. Approved, Investigational, description, a widely used non-cardioselective beta-adrenergic antagonist. PubMed: Ohnishi ST, Sadanaga KK, Katsuoka M, Weidanz WP: Effects of membrane acting-drugs on plasmodium species and sickle cell erythrocytes. Mechanism of action Propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart, inhibiting sympathetic stimulation. Absorption Propranolol is almost completely absorbed from the GI tract; however, plasma concentrations attained are quite variable among individuals. 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PubMed: Kind Protein Organism Humans Pharmacological action Unknown Actions Inhibitor General Function Serotonin binding Specific Function Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral. 2010 Jan;38(Database issue D237-43. It is owned and operated by chef Alain and his wife Beth. (S)-Warfarin The metabolism of (S)-Warfarin can be decreased when combined with Propranolol. PubMed:9760032 Choppin A, O'Connor SE: Presence of vasoconstrictor 5HT1-like receptors revealed by precontraction of rabbit isolated mesenteric artery. LD50565 mg/kg (orally in mice).
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